G-130

G-130
IUPAC命名法による物質名
	IUPAC名 2-phenyl-5,5-dimethylmorpholine;
データベースID
CAS番号;	42013-48-9
PubChem	CID: 97711
ChemSpider	88190
化学的データ
化学式	C12H17NO
分子量	191.269 g/mol
	SMILES CC1(C)NCC(OC1)C2=CC=CC=C2;
	InChI InChI=1S/C12H17NO/c1-12(2)9-14-11(8-13-12)10-6-4-3-5-7-10/h3-7,11,13H,8-9H2,1-2H3; Key:KJUOROGOOZJYAI-UHFFFAOYSA-N;
	テンプレートを表示

G-130または2-フェニル-5,5-ジメチルテトラヒドロ-1,4-オキサジン(2-Phenyl-5,5-dimethyltetrahydro-1,4-oxazine)^[1]は、フェンメトラジン系の精神刺激薬、食欲減退薬である^[2]^[3]^[4]。

構造アナログ

^ GB 1336732 - Diethanolamine Derivatives.
^ Fanelli O (June 1973). “Pharmacological and toxicological study of a new psychotropic stimulant: the 2-phenyl-5-dimethyl-tetrahydro-1,4-oxazine, in comparison with d,l-amphetamine, phenmetrazine and pemoline-Mg”. Arzneimittel-Forschung 23 (6): 810-6. PMID 4740767.
^ Fanelli O, Mazzoncini V, Ferri S (October 1974). “Toxicological and teratological study of 2-phenyl-5,5-dimethyl-tetrahydro-1,4-oxazine hydrochloride (G 130), a psychostimulant drug”. Arzneimittel-Forschung 24 (10): 1627-2. PMID 4479774.
^ Fanelli O, Mazzoncini V, Trallori L (December 1974). “Antagonism of psychostimulant 2-phenyl-5,5-dimethyl-tetrahydro-1,4-oxazine hydrochloride (G 130) to central nervous system depressing drugs. Monoamine oxidase inhibitory activity and norepinephrine and serotonin induced changes. Comparison with dL-amphetamine”. Arzneimittel-Forschung 24 (12): 2025-9. PMID 4480283.
^ “Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotine”. J. Med. Chem. 54 (5): 1441–8. (March 2011). doi:10.1021/jm1014555. PMC 3048909. PMID 21319801. https://doi.org/10.1021/jm1014555.