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Template:PBB/3976

Leukemia inhibitory factor
PDB rendering based on 1LKI.
PDBに登録されている構造
PDB Ortholog search: PDBe, RCSB, PDBj
PDBのIDコード一覧

1EMR​, 1PVH​, 2Q7N

識別記号
記号 LIF; CDF; DIA; HILDA; MLPLI
その他ID OMIM159540 MGI英語版96787 HomoloGene英語版1734 GeneCards: LIF Gene
遺伝子オントロジー
分子機能 RNA polymerase II transcription factor recruiting transcription factor activity
receptor binding
cytokine activity
leukemia inhibitory factor receptor binding
growth factor activity
細胞の構成要素 extracellular space
cytoplasm
生物学的プロセス blood vessel remodeling
immune response
multicellular organismal development
embryo implantation
positive regulation of cell proliferation
negative regulation of cell proliferation
stem cell maintenance
positive regulation of peptidyl-serine phosphorylation
positive regulation of peptidyl-serine phosphorylation of STAT protein
tyrosine phosphorylation of Stat3 protein
positive regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of MAPK cascade
positive regulation of macrophage differentiation
negative regulation of meiosis
positive regulation of transcription from RNA polymerase II promoter
decidualization
negative regulation of hormone secretion
lung alveolus development
muscle organ morphogenesis
neuron development
positive regulation of astrocyte differentiation
leukemia inhibitory factor signaling pathway
positive regulation of peptidyl-tyrosine phosphorylation
lung vasculature development
lung lobe morphogenesis
trophoblast giant cell differentiation
spongiotrophoblast differentiation
negative regulation of ERK1 and ERK2 cascade
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
regulation of metanephric nephron tubule epithelial cell differentiation
positive regulation of protein localization to nucleus
positive regulation of histone H3-K27 acetylation
出典: Amigo / EGO
RNA発現パターン
その他参照発現データ
オルソログ
ヒト マウス
Entrez英語版 3976 16878
Ensembl英語版 ENSG00000128342 ENSMUSG00000034394
UniProt英語版 P15018 P09056
RefSeq (mRNA) NM_001257135 NM_001039537
RefSeq (protein) NP_001244064 NP_001034626
Location (UCSC) Chr 22:
30.64 - 30.64 Mb
Chr 11:
4.26 - 4.27 Mb
PubMed search [1] [2]
KEGG GENES hsa:3976 mmu:16878